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Anderson
Junjie Lu.
陆俊捷.

PhD candidate in Epidemiology & Clinical Research at Stanford. I study sexual and gender minority health, mental health disparities, and causal inference methods. 斯坦福大学医学院流行病学与临床研究系的博士生,研究方向为性少数群体健康、精神健康的群体差异,以及因果推断方法。

Anderson Junjie Lu

My research interests include causal inference methods, sexuality and gender, mental and behavioral health, and integrative medicine. 我的研究兴趣包括:因果推断方法性与性别研究心理与精神卫生整合医学

I am a PhD candidate in Epidemiology and Population Health at Stanford University School of Medicine, advised by Dr. David Rehkopf. My training bridges clinical medicine (MBBS) and population health (MPH, Harvard T.H. Chan). 目前在斯坦福大学医学院攻读流行病学与人群健康博士,导师是 David Rehkopf 教授。我的学术背景横跨临床医学(MBBS)与人群健康(哈佛陈曾熙公共卫生学院 MPH)。

I work on three questions: What causes disease? How do we understand human sexuality and gender? And how can we make populations healthier? I trained in clinical medicine and traditional Chinese medicine at Shanghai Jiao Tong University and Shanghai University of Traditional Chinese Medicine, and in epidemiology at the Harvard T.H. Chan School of Public Health and Stanford. 我尝试回答:疾病发生的原因是什么?人类的性与性别是怎样的现象?我们如何让人口更健康?我先后在上海交通大学与上海中医药大学接受临床医学中医学的训练,在哈佛陈曾熙公共卫生学院与斯坦福大学接受流行病学的训练。

Main areas.主要领域。

I.

Sexual & gender minority health性与性别少数群体健康

Quantifying health disparities for SGM populations and the structural forces that produce them. 量化性少数群体的健康差异,以及塑造这些差异的结构性因素。

  • All of Us — 270k participantsAll of Us 队列· 约 27 万人
  • NHANES 2005–2014NHANES 2005–2014
  • Minority stress & stigma少数压力与污名
II.

Mental health精神健康

Depression, anxiety, PTSD — and the biological and social factors that modify risk. 拑郁、焦虑、创伤后应激障碍,以及影响这些风险的生物与社会因素。

  • Marginal structural models边际结构模型
  • Effect modification效应修饰
  • Biomarkers & neuroimaging生物标志物与神经影像
III.

Causal inference methods因果推断方法

Frameworks that make observational studies more trustworthy, especially for exposures that resist tidy counterfactual definitions. 让观察性研究更值得信赖的方法框架,尤其适用于那些难以用清晰反事实加以定义的暴露变量。

  • Counterfactual frameworks反事实框架
  • Inverse probability weighting逆概率加权
  • Mediation analysis中介效应分析

Peer-reviewed work.同行评审论文。

10 publications10 篇论文
  • 2026

    SSM - Mental Health · Methods applicationSSM - Mental Health · 方法学应用 In press即将刊出

    Estimating Depression Risk Differences Between Sexual Minority and Heterosexual Young Adults Using Targeted Maximum Likelihood Estimation and Super Learner用靶向最大似然估计与 Super Learner 估计性少数与异性恋青年人群的抑郁风险差异

    Lu JA, Rehkopf DH, Odden MC.

    A non-technical introduction to TMLE and Super Learner for public health researchers, applied to sexual minority mental health. Using Add Health (Waves 1–4), we compared IPTW, G-computation, and TMLE across 35 modeling scenarios and found depression risk differences between sexual minority and heterosexual young adults of 6.0%–8.9%, with consistent estimates across methods and sensitivity checks.面向公共卫生研究者的 TMLE 与 Super Learner 入门性介绍,并将方法应用于性少数人群的精神健康研究。基于 Add Health 第 1–4 轮数据,我们在 35 种建模情境中比较了 IPTW、G-computation 与 TMLE,发现性少数与异性恋青年人群的抑郁风险差异为 6.0%–8.9%,各种方法与敏感性分析结果一致。

    3,342
    Add Health participantsAdd Health 参与者
    6.0–8.9%
    Depression risk difference抑郁风险差异
    35
    Modeling scenarios建模情境数
    3
    Estimators compared比较的估计方法
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  • 2026

    Archives of Sexual Behavior · Interrupted time seriesArchives of Sexual Behavior · 中断时间序列分析 In press即将刊出

    China's 2017 Censorship Policy and Attitudes Towards Same-Sex Behavior: An Interrupted Time Series Analysis中国 2017 年审查政策与同性行为态度:一项中断时间序列分析

    Lu J, Rehkopf DH, Bendavid E.

    Did China's 2017 regulation restricting media portrayals of sexual and gender minorities shift how people feel about same-sex behavior? Using interrupted time series analysis on seven waves of the Chinese General Social Survey, we find the policy was followed by a sharp near-term drop in positive attitudes — sharpest among men — and diverging longer-term trajectories between frequent and infrequent internet users.中国 2017 年限制性少数群体媒体呈现的审查政策,是否改变了公众对同性行为的态度?我们用中国综合社会调查(CGSS)七轮数据做了中断时间序列分析,发现政策出台后正面态度短期内显著下降(男性降幅更大),而从长期看,频繁使用互联网与较少使用互联网的人群态度走势发生了明显分化。

    66,057
    Respondents, 2010–2021受访者,2010–2021
    0.73×
    Odds of positive attitudes post-policy政策后正面态度比值比
    38%
    Larger drop among men男性正面态度下降幅度
    7
    Survey waves analyzed纳入分析的调查轮次
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  • 2025

    JAMA Network Open · Cross-sectional studyJAMA Network Open · 横断面研究 Featured精选

    Mental Health Disparities by Sexual Orientation and Gender Identity in the All of Us Research ProgramAll of Us 研究项目中的性取向、性别认同与精神健康差异

    Lu JA, Soltani S, Austin SB, Rehkopf DH, Lunn MR, Langston ME.

    The largest national analysis to date of mental health across sexual orientation and gender identity. Using linked electronic health records from All of Us, we found sexual and gender minority adults had markedly elevated odds of bipolar disorder, PTSD, depression, and ADHD — disparities we interpret as the footprint of stigma and minority stress, not identity.截至目前,这是规模最大的一项全美国性研究,归纳了性取向与性别认同与精神健康的关系。基于 All of Us 队列的电子病历数据,我们发现性少数人群出现双相障碍、创伤后应激障碍、拑郁和注意力缺陷多动障碍的几率明显升高。我们认为,这种差异反映的是社会污名和少数压力,而不是身份本身。

    269,947
    Participants参与者
    8.2%
    SGM-identified性少数身份比例
    3.67×
    PTSD odds, gender-diverse AFAB出生指派女性性别多元人群 PTSD 几率
    10
    Conditions studied纳入分析的病症数
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  • 2025

    Working paper · Stanford University工作论文 · 斯坦福大学

    Towards Causal Interpretation of Sexual Orientation in Regression Analysis回归分析中“性取向”变量的因果解读

    Lu J, Guo Z, Rehkopf DH.

    A methods paper arguing that “sexual orientation” is not one variable but three — attraction, behavior, and identity — and that research must define which one it means. We illustrate with NHIS data and find a direct effect of SGM status on depression that does not run through social support.一篇方法学论文。研究者通常把“性取向”当作一个变量,但它其实包含三个维度——吸引、行为与身份认同,做研究时必须明确自己指的是哪一个。我们以 NHIS 数据为例发现,性少数身份对拑郁的影响是直接的,并未〇通过社会支持起中介作用。

    3.07×
    Direct effect on depression抑郁的直接效应
    1.07×
    Indirect via social support经社会支持的间接效应
    3
    Exposure domains defined界定的暴露维度
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  • 2024

    American Journal of Preventive Medicine · 67(6):811–819American Journal of Preventive Medicine · 67(6):811–819

    Impact of Digital Advertising Policy on Harmful Product Promotion: NLP Analysis of Skin-Lightening Ads数字广告政策对有害产品推广的影响:美白广告的自然语言处理分析

    Lu J, Chua SN, Kavanaugh JR, Prashar J, Ndip-Agbor E, Santoso M, Jackson DA, Chakraborty P, Raffoul A, Austin SB.

    Did Google’s 2022 policy against discriminatory skin-lightening ads actually change what ran? We trained a Vertex AI language model on ads from eight countries and measured content shifts two weeks before vs. after enforcement — finding real, measurable drops in the labels the policy targeted.谷歌 2022 年禁止歧视性美白广告的政策,是否真的改变了广告投放的内容?我们用八个国家的广告样本训练了一个 Vertex AI 语言模型,对比政策执行前后两周的内容变化,结果发现政策所针对的标签确实出现了可观察的下降。

    5,236
    Ads analyzed分析广告数
    8
    Countries国家数
    −47%
    Race/ethnic labels种族/族裔标签
    0.87
    Model F1 score模型 F1 分数
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  • 2024

    Journal of Affective Disorders Reports · 15:100714Journal of Affective Disorders Reports · 15:100714

    Childhood adversity severity modulates adaptive psychological and amygdala volumetric changes after behavioral interventions童年逆境的严重程度,如何影响行为干预后的心理适应与杏仁核体积变化

    Joss D, Lu J, Teicher MH, Lazar SW.

    A randomized trial asking whether mindfulness changes the brain differently for adults who survived childhood adversity. Among those with more severe early trauma, shifts in mindfulness and anxiety tracked with measurable changes in amygdala volume — a biomarker of stress reactivity.一项随机对照试验:正念训练对经历过童年逆境的成年人是否会带来不同的大脑变化?在童年创伤更严重的人群中,正念水平与焦虑的改变伴随着杏仁核体积的显著变化——这是一项反映应激反应性的生物标志物。

    64
    Randomized随机入组
    8wk
    Intervention干预周期
    MRI
    Pre / post brain imaging前后脑影像
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  • 2023

    Journal of Affective Disorders · 341:202–210Journal of Affective Disorders · 341:202–210

    Marginal structural model analysis of cancer diagnosis history, education, and major depressive symptoms癌症诊断史、教育水平与重度抑郁症状的边际结构模型分析

    Liu L, Lu J, Yang J, Dong Y, Yin P, Chen Y.

    A recent cancer diagnosis nearly quadrupled the odds of major depressive disorder in the next year — but only among adults whose education stopped at high school. Education appears to buffer the psychological toll of a cancer diagnosis in ways clinical care has not caught up with.確诊癌症后一年内,重度抑郁障碍的发生几率几乎翻了四倍——但这种翻倍效应只出现在教育水平止于高中的成年人当中。教育似乎在缓冲着癌症诊断带来的心理冲击,而目前的临床护理还没能跟上这一点。

    7,108
    MIDUS participantsMIDUS 参与者
    3.74×
    MDD odds, 1yr post-Dx确诊后一年 MDD 几率
    3.45×
    Among less-educated教育程度较低人群
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  • 2023

    BMC Public Health · 23:294BMC Public Health · 23:294

    Depressive symptoms and White Blood Cell count across sexual minority subgroups性少数人群中抑郁症状与白细胞计数的关系

    Lu J, Yang J, Liang J, Mischoulon D, Nyer M.

    Sexual minority adults report more depressive symptoms than heterosexual peers — but do their bodies show it? We examined white blood cell count, a crude marker of systemic inflammation, across subgroups including those uncertain about their orientation, a population rarely studied separately.性少数群体报告的抑郁症状要多于异性恋群体——但这一点会不会在身体层面留下痕迹?我们考察了白细胞计数这一粗略的全身炎症指标,并单独分析了“性取向不确定”这一常被忽视的亚群。

    14,090
    NHANES participantsNHANES 参与者
    10yrs
    Data span 2005–14数据年份 2005–14
    WBC
    Biological readout生物读出
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  • 2023

    Journal of Affective Disorders · 327:226–229Journal of Affective Disorders · 327:226–229

    HSV-2 infection and depressive symptoms across sex and sexual minority groupsHSV-2 感染与抑郁症状:性别及性少数群体间的差异

    Lu J, Liang J, Yang J, Mischoulon D, Nyer M.

    Herpes simplex 2 has been tied to depression, but for whom most? In a nationally representative sample, the association was meaningfully stronger among women than men — a sex-specific effect that points toward where clinical screening for post-infection mood symptoms might matter most.HSV-2 与抑郁存在关系,但这一关系在谁身上最为明显?在一个全美国代表性样本中,我们发现女性中的关系显著强于男性——这种性别差异提示临床可能需要对感染后情绪症状采取有针对性的筛查。

    57,684
    NHANES participantsNHANES 参与者
    1.43×
    Depression odds, women女性抑郁几率
    1.20×
    Depression odds, men男性抑郁几率
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  • 2026

    BMC Public Health · 26:140BMC Public Health · 26:140

    Minority-group ethnicity and self-reported health outcomes in China, 2010–2021中国少数民族身份与自评健康状况,2010–2021

    Lu J, et al. (Rehkopf DH, senior)

    The first multi-wave national analysis of ethnic health disparities in China, framed through ecosocial theory. Using seven waves of the Chinese General Social Survey, we separate individual, institutional, and regional forces shaping self-reported health between Han and ethnic-minority populations.这是首份基于生态社会理论视角、跨多轮数据考察中国民族间健康差异的全国性研究。我们用中国综合社会调查(CGSS)七个轮次的数据,拆解了影响汉族与少数民族自评健康差距的个人、制度与地区三个层面的因素。

    66,057
    Respondents受访者
    7
    Waves, 2010–2021调查轮次 2010–2021
    3
    Health outcomes modeled建模健康结局数
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  • 2023

    Study protocol · Randomized single-blinded trial研究方案 · 单盲随机对照试验

    Auricular Acupressure for Primary Dysmenorrhea: Study Protocol for a Randomized Trial耳穴按压治疗原发性痛经:一项单盲随机对照试验的研究方案

    Liu L, Hu J, Lu J, Yang J.

    A protocol for a single-blinded RCT testing ear-based acupressure against a sham control for menstrual pain — evaluating immediate analgesia, time-effect relationship, and whether it reduces reliance on ibuprofen.一项单盲随机对照试验方案:以假对照为基准,评估耳穴按压对经期疼痛的治疗效果、即时镇痛效应、时间-效应关系,以及能否减少对布洛芬的依赖。

    92
    Planned enrollment计划入组
    1:1
    Allocation分组比例
    VAS
    Primary outcome主要结局
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When the research meets the public.当研究进入公共视野。

U.S. News & World Report · Feb. 20, 2025《美国新闻与世界报道》 · 2025年2月20日

“LGBTQ+ Stress and Stigma Increase Risk of Mental Health Problems “LGBTQ+ 群体所承受的压力与污名,增加了精神健康问题的风险”

HealthDay and U.S. News covered our JAMA Network Open analysis of 270,000 All of Us participants — emphasizing that these disparities reflect stigma and minority stress, not SGM identity itself. HealthDay 与 U.S. News 报道了我们发表于 JAMA Network Open 的研究——一项涵盖了 All of Us 队列 27 万名参与者的数据分析——强调这些差异反映的是污名与少数压力,而不是性少数身份本身。

U.S. NEWS · HEALTH NEWS
LGBTQ+ Stress and Stigma Increase Risk of Mental Health Problems
By HealthDay — Feb. 20, 2025

Explaining complex epidemiology in plain language, and giving research back to the people it should serve.用简单的语言讲述复杂的流行病学概念,让研究回到它应该惠及的人。

I work to translate complex epidemiologic findings into plain language for the public. The questions I study come from people who need help — and the answers should ultimately come back to them. 我致力于把复杂的流行病学研究结论用通俗易懂的语言传递给大众。同时,研究课题不仅来自需要帮助的人,也最终造福于需要帮助的人。

Putting research into people's hands.健康教育资源。

Interactive guide · 2026交互式指南 · 2026

A gender-inclusive cancer screening guide for the waiting room. 为候诊室设计的性别包容癌症筛查指南。

A patient-facing tool that asks about a person's body and history — not their gender — and produces a personalized list of recommended cancer screenings. Designed to help transgender and gender-diverse patients receive the screenings they actually need, before they walk into clinic. 一款面向患者的工具:不预设性别,而是基于身体器官与个人史,为每位用户生成个性化的癌症筛查建议。希望帮助跨性别与性别多元人群在走进诊室之前,了解自己真正需要做的筛查项目。

Step 4 of 10第 4 步 / 共 10 步
Which describes your body?下列哪项描述你的身体
Has a cervix有子宫颈
Has a prostate有前列腺
Has breast tissue有乳腺组织
Prefer not to say不想回答
Available in 14 languages支持 14 种语言

Get in touch.常联系。

Email邮箱
Affiliation院系
Department of Epidemiology &
Population Health
流行病学与
人群健康系
Institution机构
Stanford University
School of Medicine
斯坦福大学
医学院
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